Manuka Health's Natural Toothpaste combines three proven natural oral hygiene ingredients: BIO30 New Zealand Propolis, MGO 400+ Manuka Honey and pure Tea Tree Oil. BIO30 NZ Propolis is exceptionally high in bioflavonoids, contributing to this advanced oral health formula. MGO 400+ Manuka Honey and Tea Tree Oil are combined to promote healthy teeth and gums. This toothpaste contains no fluoride or preservatives and has never been tested on animals. Essential oils and herbs have been added to provide great taste and leave teeth feeling fresh and clean.